LFHP-1c is an PGAM5 inhibitor with neuroprotective activity in brain ischemic stroke. LFHP-1c protects blood-brain barrier integrity from ischemia-induced injury. LFHP-1c binds to endothelial PGAM5 to inhibit the activity of PGAM5 phosphatase and the interaction of PGAM5 with NRF2. LFHP-1c exhibits in vitro and in vivo protection[1].
Molecular Weight:
873.13
Purity:
98.01
CAS Number:
[2102347-47-5]
Formula:
C55H64N6O4
Target:
Phospholipase
Application Notes:
MCE Product type: Reference compound1
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