Navlimetostat is a potent, orally active, selective PRMT5-MTA complex inhibitor, with IC50 of 3.6 and 20.5 nM for PRMT5-MTA and PRMT5. Navlimetostat binds to the PRMT5-MTA complex, with KD value of 0.14 pM. Navlimetostat shows antineoplastic activity in vitro and in vivo, and can be used for cancer study[1][2].
Molecular Weight:
464.88
Purity:
99.28
CAS Number:
[2630904-45-7]
Formula:
C23H18ClFN6O2
Target:
Histone Methyltransferase
Application Notes:
MCE Product type: Reference compound
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