Navlimetostat (hydrochloride)

Product Overview

• Article Name: Navlimetostat (hydrochloride)
• Biozol Catalog Number: MCE-HY-139611C
• Supplier Catalog Number: HY-139611C
• Alternative Catalog Number: MCE-HY-139611C-5MG,MCE-HY-139611C-25MG,MCE-HY-139611C-10MG,MCE-HY-139611C-100MG,MCE-HY-139611C-10MMX1ML,MCE-HY-139611C-50MG,MCE-HY-139611C-1MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: MRTX-1719 (hydrochloride), BMS-986504 (hydrochloride)

Product Description

Navlimetostat hydrochloride is a potent, orally active, selective PRMT5-MTA complex inhibitor, with IC50s of 3.6 and 20.5 nM for PRMT5-MTA and PRMT5. Navlimetostat hydrochloride binds to the PRMT5-MTA complex, with KD value of 0.14 pM. Navlimetostat shows antineoplastic activity in vitro and in vivo, and can be used for cancer study[1][2].

Product Properties

• Molecular Weight: 501.34
• Purity: 99.61
• Formula: C23H19Cl2FN6O2
• Target: Histone Methyltransferase

Application Notes

• Application Notes: MCE Product type: Reference compound