(S)-GSK-3685032 is the isomer of GSK-3685032 (HY-139664), and can be used as an experimental control. GSK-3685032 is a non-time-dependent, noncovalently, first-in-class reversible DNMT1-selective inhibitor, with an IC50 of 0.036 µM. GSK-3685032 induces robust loss of DNA methylation, transcriptional activation, and cancer cell growth inhibition[1].
Molecular Weight:
420.53
Purity:
98.82
CAS Number:
[2170142-58-0]
Formula:
C22H24N6OS
Target:
DNA Methyltransferase
Application Notes:
MCE Product type: Reference compound1
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