alpha5beta1 integrin agonist-1 is an alpha5beta1 integrin agonist, with an EC50 of 1.5 nM. alpha5beta1 integrin agonist-1 inhabits alpha4beta1 integrin (IC50 = 2.99 µM) in Jurkat/VCAM-1 adhesion assayalpha5beta1 integrin agonist-1 induces concentration-dependent apoptosis and activates the caspase 3/7 pathway in alpha5beta1 integrin-expressing K562 cancer cells. alpha5beta1 integrin agonist-1 can be used for the study of cancer[1].
Molecular Weight:
547.49
Purity:
99.67
CAS Number:
[2756557-83-0]
Formula:
C24H26FN5O9
Target:
Apoptosis,Caspase,Integrin
Application Notes:
MCE Product type: Reference compound
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