Donidalorsen (ISIS-721744, IONIS-PKK-LRX free acid) is an antisense oligonucleotide targeting prekallikrein (PKK). Donidalorsen inhibits kallikrein activity and reduces the production of Bradykinin (HY-P0206) by specifically binding to and degrading PKK mRNA in the liver. Donidalorsen can be used in the research of hereditary angioedema[1][2].
Molecular Weight:
8672.64
CAS Number:
[2304692-48-4]
Formula:
C296H435N83O151P20S15
Target:
Kallikrein
Application Notes:
MCE Product type: Oligonucleotides
* VAT and and shipping costs not included. Errors and price changes excepted