MPO-IN-1 is a potent, orally active, and irreversible indole-containing inhibitor of myeloperoxidase (MPO). MPO-IN-1 has IC50s of 2.6 µM and 5.3 µM for MPO and thyroid peroxidase (TPO), respectively. MPO-IN-1 inhibits MPO activity in an acute mouse model of inflammation[1].
Molecular Weight:
400.90
Purity:
98.07
CAS Number:
[2471981-21-0]
Formula:
C24H21ClN4
Target:
Glutathione Peroxidase
Application Notes:
MCE Product type: Reference compound
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