LeuRS-IN-1 hydrochloride is a potent, orally active M. tuberculosis leucyl-tRNA synthetase (M.tb LeuRS) inhibitor. LeuRS-IN-1 hydrochloride has IC50 and Kd values of 0.06 µM, 0.075 µM for M.tb LeuRS, respectively[1]. LeuRS-IN-1 hydrochloride inhibits human cytoplasmic LeuRS (IC50=38.8 µM), and HepG2 protein synthesis (EC50=19.6 µM)[2].
Molecular Weight:
277.94
CAS Number:
[1364683-67-9]
Formula:
C10H14BCl2NO3
Target:
Bacterial
Application Notes:
MCE Product type: Reference compound
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