NBD-14270, a pyridine analogue, is a potent HIV-1 entry antagonist with an IC50 of 180 nM against 50 HIV-1 Env-pseudotyped viruses. NBD-14270 binds to HIV-1 gp120 and shows potent antiviral activity. NBD-14270 shows low cytotoxicity (CC50>100 µM)[1][2].
Molecular Weight:
425.43
Purity:
99.53
CAS Number:
[2411819-82-2]
Formula:
C18H18F3N5O2S
Target:
HIV
Application Notes:
MCE Product type: Reference compound
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