Methyltetrazine-DBCO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Methyltetrazine-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Methyltetrazine-DBCO also contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
Molecular Weight:
683.73
Purity:
95.22
CAS Number:
[1802238-48-7]
Formula:
C34H33N7O7S
Target:
ADC Linker
Application Notes:
MCE Product type: ADC Related
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