Pomalidomide-PEG4-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1]. Pomalidomide-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Molecular Weight:
518.52
Purity:
99.85
CAS Number:
[2271036-47-4]
Formula:
C23H30N6O8
Target:
E3 Ligase Ligand-Linker Conjugates
Application Notes:
MCE Product type: Reference compound
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