R121919 (NBI30775) is a potent and selective CRF1R antagonist with a Ki of 2 to 5 nM. R121919 has antidepressant and anxiolytic effects. R121919 alleviates defensive withdrawal in rats[1][2][3].
Molecular Weight:
380.53
Purity:
99.66
CAS Number:
[195055-03-9]
Formula:
C22H32N6
Target:
CRFR
Application Notes:
MCE Product type: Reference compound
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