NRX-2663 is an enhancer of the interaction between beta-catenin, and its cognate E3 ligase, SCFbeta-TrCP. NRX-2663 enhances the binding of beta-catenin peptide for beta-TrCP with an EC50 of 22.9 µM and a Kd of 54.8 nM[1].
Molecular Weight:
418.32
Purity:
98.20
CAS Number:
[2763260-34-8]
Formula:
C20H13F3N2O5
Target:
E1/E2/E3 Enzyme,beta-catenin
Application Notes:
MCE Product type: Reference compound
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