RM-018 is a potent, functionally distinct tricomplex KRASG12C active-state inhibitor. RM-018 retains the ability to bind and inhibit KRASG12C/Y96D and could overcome resistance. RM-018 binds specifically to the GTP-bound, active [''RAS(ON)] state of KRASG12C[1].
Molecular Weight:
985.22
Purity:
95.50
CAS Number:
[2641993-55-5]
Formula:
C56H72N8O8
Target:
Ras
Application Notes:
MCE Product type: Reference compound
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