ART558 is a potent, selective and allosteric DNA polymerase theta (Poltheta) inhibitor (IC50=7.9 nM). ART558 elicits BRCA-gene synthetic lethality and DNA damage. ART558 can be used for the research of cancer, such as breast cancer[1].
Molecular Weight:
418.41
Purity:
99.97
CAS Number:
[2603528-97-6]
Formula:
C21H21F3N4O2
Target:
DNA/RNA Synthesis
Application Notes:
MCE Product type: Reference compound
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