Vociprotafib (RMC-4630) is an orally active, selective and potent phosphatase SHP2 inhibitor, which blocks activation of the RAS-RAF-MEK-ERK signaling pathway with antitumor activity. Vociprotafib accelerates the time to, and increases the magnitude of, tumor regressions in Osimertinib (HY-15772)-sensitive EGFR-mutant tumors of mice[1][2][3].
Molecular Weight:
450.99
Purity:
99.70
CAS Number:
[2172652-48-9]
Formula:
C20H27ClN6O2S
Target:
Phosphatase,SHP2
Application Notes:
MCE Product type: Reference compound
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