INCB059872 is a potent, orally active, selective and irreversible Lysine-Specific Demethylase 1 (LSD1) inhibitor that achieves inhibitory activity through the formation of covalent FAD-adducts. INCB059872 can inhibit cell proliferation and induce cell differentiation by upregulating the expression of myeloid differentiation markers CD86 and CD11b. INCB059872 can be used for the research of myeloid leukemia[1].
Molecular Weight:
386.53
Purity:
99.60
CAS Number:
[1802909-49-4]
Formula:
C23H34N2O3
Target:
Histone Demethylase
Application Notes:
MCE Product type: Reference compound
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