Bexarotene (LGD1069) is a high-affinity and selective retinoid X receptors (RXR) agonist with EC50s of 33, 24, 25 nM for RXRalpha, RXRbeta, and RXRgamma, respectively. Bexarotene shows limited affinity for RAR receptors (EC50 >10000 nM)[1][2][3]. Bexarotene can be used for the research of cutaneous T-cell lymphoma.
Molecular Weight:
348.48
Purity:
99.90
CAS Number:
[153559-49-0]
Formula:
C24H28O2
Target:
Autophagy,RAR/RXR
Application Notes:
MCE Product type: Reference compound
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