Compound E is a gamma-secretase inhibitor. Compound E blocks beta-amyloid(40), beta-amyloid(42), and Notch gamma-secretase cleavage with IC50s of 0.24, 0.37, 0.32 nM, respectively.
Molecular Weight:
490.50
Purity:
99.97
CAS Number:
[209986-17-4]
Formula:
C27H24F2N4O3
Target:
gamma-secretase
Application Notes:
MCE Product type: Reference compound
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