PPQ-102 (CFTR Inhibitor) is a reversible CFTR inhibitor that completely inhibits CFTR chloride currents (IC50 ~90 nM). PPQ-102 is not affected by membrane potential-dependent cell allocation or blocking efficiency (uncharged at physiological pH) and effectively prevents cyst enlargement in polycystic kidney disease[1].
Molecular Weight:
438.48
Purity:
99.73
CAS Number:
[931706-15-9]
Formula:
C26H22N4O3
Target:
CFTR
Application Notes:
MCE Product type: Reference compound
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