MS33 is a potent WDR5 degrader, with Kds of 870 nM and 120 nM for VCB and WDR5, respectively. MS33 induces WDR5 degradation in an E3 ligase VHL, and proteasome-dependent manner. MS33 can be used for the research of acute myeloid leukemia[1][2][3].
Molecular Weight:
1208.48
Purity:
99.3800
CAS Number:
[2407449-11-8]
Formula:
C64H84F3N11O7S
Target:
Histone Methyltransferase,PROTACs,WDR5
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
