Vernakalant hydrochloride is a mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker. IC50 for block by Vernakalant of wild-type and mutant Kv1.5 channels Fractional block is 13.350.93 µM, 0.610.03 µM, and 1.630.09 µM for Kv1.5 channelwt, Kv1.5 channelI508F, Kv1.5 channelT479A, respectively.
Molecular Weight:
385.93
Purity:
99.33
CAS Number:
[748810-28-8]
Formula:
C20H32ClNO4
Target:
Potassium Channel
Application Notes:
MCE Product type: Reference compound
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