STF-1084 is a specific, cell-impermeable, competitive inhibitor of ENPP1 (Ki = 33 nM). STF-1084 increases extracellular cGAMP concentrations by preventing its degradation by ENPP1, thereby enhancing immune infiltration. STF-1084 acts synergistically with ionizing radiation (IR) and cGAMP to delay tumor progression. STF-1084 can be used to study cancers with low immunogenicity[1].
Molecular Weight:
381.36
Purity:
99.7
CAS Number:
[2298390-71-1]
Formula:
C17H24N3O5P
Target:
Phosphodiesterase (PDE)
Application Notes:
MCE Product type: Reference compound
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