MMV666810, a 2-aminopyrazine similar to MMV390048, is potent against asexual parasites at 5.94 nM, but against gametocytes, it has a 3.3-fold selectivity to late-stage gametocytes compared to earlier stages (early-stage gametocyte: IC50 603 88 nM, late-stage gametocyte: IC50 179 8 nM).
Molecular Weight:
442.43
CAS Number:
[1450666-97-3]
Formula:
C23H21F3N4O2
Target:
Parasite
Application Notes:
MCE Product type: Reference compound
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