GNE-9815, CAS [[2729996-45-4]]

Product Overview

• Article Name: GNE-9815, CAS [[2729996-45-4]]
• Biozol Catalog Number: MCE-HY-142160
• Supplier Catalog Number: HY-142160
• Alternative Catalog Number: MCE-HY-142160-100MG,MCE-HY-142160-10MMX1ML,MCE-HY-142160-50MG,MCE-HY-142160-10MG,MCE-HY-142160-5MG,MCE-HY-142160-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

GNE-9815 (compound 7) is a highly selective, pan-RAF inhibitor with good oral bioavailability. GNE-9815 exhibits Ki values of 0.062 and 0.19 nM for CRAF and BRAF, respectively. GNE-9815 combines with MEK inhibitor Cobimetinib (HY-13064) shows synergistic modulation of MAPK pathway. GNE-9815 can be used in studies of KRAS mutant cancers[1].

Product Properties

• Molecular Weight: 455.48
• Purity: 98.94
• CAS Number: [2729996-45-4]
• Formula: C26H22FN5O2
• Target: Raf

Application Notes

• Application Notes: MCE Product type: Reference compound