Crisugabalin, CAS [[2209104-84-5]]

Product Overview

• Article Name: Crisugabalin, CAS [[2209104-84-5]]
• Biozol Catalog Number: MCE-HY-142240
• Supplier Catalog Number: HY-142240
• Alternative Catalog Number: MCE-HY-142240-5MG,MCE-HY-142240-10MG,MCE-HY-142240-50MG,MCE-HY-142240-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: HSK16149

Product Description

Crisugabalin is an orally active, selective ligand for the alpha2delta subunit of voltage-gated calcium channels, with a target IC50 of 3.96 nM in rats. Crisugabalin inhibits the binding of [3H]gabapentin to the alpha2delta subunit, reduces calcium influx, decreases neuronal excitability, and impairs nociceptive transmission. Crisugabalin alleviates mechanical allodynia, neuropathic pain and inflammatory pain in rats, and reduces phase II pain behaviors. Crisugabalin can be used in research related to chronic pain, neuropathic pain, diabetic neuropathy, fibromyalgia, inflammatory pain, diabetic peripheral neuropathy and postherpetic neuralgia.

Product Properties

• Molecular Weight: 209.28
• Purity: 99.88
• CAS Number: [2209104-84-5]
• Formula: C12H19NO2
• Target: Calcium Channel

Application Notes

• Application Notes: MCE Product type: Reference compound