Dapivirine (TMC120), the prototype of diarylpyrimidines (DAPY), is an orally active and nonnucleoside reverse transcriptase inhibitor (NRTI). Dapivirine (TMC120) binds directly to HIV-1 reverse transcriptase. Dapivirine (TMC120) regulates autophagy and induced Akt, Bad and SAPK/JNK activations[1][2].
Molecular Weight:
329.41
Purity:
99.80
CAS Number:
[244767-67-7]
Formula:
C20H19N5
Target:
Apoptosis,Autophagy,HIV,Reverse Transcriptase
Application Notes:
MCE Product type: Reference compound
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