Carboxylesterase-IN-2 (compound 4u) is a potent inhibitor of Carboxylesterase Notum with an IC50 less than or equal to 10 nM. Notum is a negative regulator of Wnt signaling acting through the hydrolysis of a palmitoleoylate ester, which is required for Wnt activity. Carboxylesterase-IN-2 has the potential for the research of cancer disease[1].
Molecular Weight:
272.33
Purity:
99.91
CAS Number:
[2764748-88-9]
Formula:
C13H12N4OS
Target:
Carboxylesterase (CES),Wnt
Application Notes:
MCE Product type: Reference compound
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