CDK6/PIM1-IN-1 (hydrochloride), CAS [[2677026-15-0]]
Catalog Number:
MCE-HY-142696A
| Article Name: |
CDK6/PIM1-IN-1 (hydrochloride), CAS [[2677026-15-0]] |
| Biozol Catalog Number: |
MCE-HY-142696A |
| Supplier Catalog Number: |
HY-142696A |
| Alternative Catalog Number: |
MCE-HY-142696A-10MG,MCE-HY-142696A-100MG,MCE-HY-142696A-25MG,MCE-HY-142696A-5MG,MCE-HY-142696A-50MG |
| Manufacturer: |
MedchemExpress |
| Category: |
Biochemikalien |
| CDK6/PIM1-IN-1 (Compound 51) hydrochloride is an orally active and potent dual CDK6/PIM1 inhibitor with IC50 values of 39 and 88 nM, respectively. CDK6/PIM1-IN-1 hydrochloride inhibits CDK4 (IC50=3.6 nM). CDK6/PIM1-IN-1 hydrochloride significantly inhibits acute myeloid leukemia (AML) cell proliferation, arrest cell cycle at the G1 phase, and promote cell apoptosis. CDK6/PIM1-IN-1 exhibits potent anti-AML activity[1]. |
| Molecular Weight: |
510.01 |
| Purity: |
99.38 |
| CAS Number: |
[2677026-15-0] |
| Formula: |
C25H29ClFN9 |
| Target: |
Apoptosis,CDK,Pim |
| Application Notes: |
MCE Product type: Reference compound |
