TPE-MI (Tetraphenylethene maleimide) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasitesPlasmodium falciparum [1][2].
Molecular Weight:
441.52
Purity:
98.93
CAS Number:
[1245606-71-6]
Formula:
C31H23NO2
Target:
Huntingtin,Parasite
Application Notes:
MCE Product type: Dye Reagents
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