ATX inhibitor 11 (compound 13c) is a potent ATX (autotaxin) inhibitor, with an IC50 of 2.7 nM. ATX inhibitor 11 can typically alleviate the severity of fibrosis tissues and effectively reduce the deposition of fibrotic biomarker alpha-SMA in mice fibrosis model. ATX inhibitor 11 can be used for lung fibrosis research[1].
Molecular Weight:
585.65
Purity:
99.44
CAS Number:
[2485779-27-7]
Formula:
C32H35N5O6
Target:
Phosphodiesterase (PDE)
Application Notes:
MCE Product type: Reference compound
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