L-745870 hydrochloride is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 hydrochloride shows weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites and alpha-adrenoceptors[1][2][3].
Molecular Weight:
363.28
Purity:
99.91
CAS Number:
[1173023-36-3]
Formula:
C18H20Cl2N4
Target:
Dopamine Receptor
Application Notes:
MCE Product type: Reference compound1
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