FLT3-IN-13 (compound 20) is a potent and effective antileukemic topoisomerase II and FLT3 dual inhibitor with IC50 values of 2.26 µM and 2.26 µM, respectively. FLT3-IN-13 arrests cell cycle at G2/M phase and induce apoptosis. FLT3-IN-13 has anticytotoxic activity, particularly against leukemia[1].
Molecular Weight:
342.35
Formula:
C20H14N4O2
Target:
Apoptosis,FLT3,Topoisomerase
Application Notes:
MCE Product type: Reference compound1
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