OYYF-175, an antimicrobial antifolate, is a dihydrofolate reductase (DHFR) inhibitor with an IC50 of 2.36 nM for Escherichia coli DHFR. OYYF-175 exhibits potent broad-spectrum antibacterial activities, especially against multi-drug resistant Gram-Negative-strains[1].
Molecular Weight:
307.32
CAS Number:
[65829-22-3]
Formula:
C17H14FN5
Target:
Bacterial
Application Notes:
MCE Product type: Reference compound
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