KLYP961 is a selective and orally active dual inhibitor of inducible and neuronal NO synthase (IC50 = 50-400 nM). KLYP961 can inhibit endotoxin-evoked plasma nitrates increases and attenuate pain behaviors in a mouse formalin model. KLYP961 can attenuate carrageenin-induced edema and inflammatory hyperalgesia and writhing response elicited by Phenylbenzoquinone (HY-W275039). KLYP961 can be used for the research of neurological disease[1].
Molecular Weight:
367.35
CAS Number:
[1125746-49-7]
Formula:
C19H15F2N5O
Target:
NO Synthase
Application Notes:
MCE Product type: Reference compound
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