MK 1256 is a highly selective and orally active inhibitor of tissue protease K (Cat K) with an IC50 of 0.62 nM. MK 1256 shows extremely high selectivity towards other tissue proteases (all > 1100 times), with only a slightly lower selectivity for tissue protease F (Cat F) (110 times). MK 1256 exhibits strong anti-bone resorption activity in the osteoporosis model of rhesus monkeys with ovariectomy. MK 1256 can be used for research on osteoporosis[1].
Molecular Weight:
563.42
CAS Number:
[919109-76-5]
Formula:
C23H23Cl2F3N4O3S
Target:
Cathepsin
Application Notes:
MCE Product type: Reference compound1
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