LG308 is a novel synthetic compound with antimicrotubule activity. LG308 induces mitotic phase arrest and inhibits G2/M progression significantly which is associated with the upregulation of cyclin B1 and mitotic marker MPM-2 and the dephosphorylation of cdc2. LG308 also induces apoptosis and cell death. LG308 significantly suppresses tumor growth. LG308 with antimitotic activity has the potential for the research of prostate cancer[1].
Molecular Weight:
308.35
CAS Number:
[1428341-65-4]
Formula:
C19H17FN2O
Target:
Apoptosis,Microtubule/Tubulin
Application Notes:
MCE Product type: Reference compound
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