Allolithocholic acid (Standard), CAS [[2276-94-0]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-143712R
Supplier Catalog Number:
HY-143712R
Alternative Catalog Number:
MCE-HY-143712R-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Allolithocholic acid (Standard) is the analytical standard of Allolithocholic acid (HY-143712). This product is intended for research and analytical applications. Allolithocholic acid is an orally active metabolite of Lithocholic acid (HY-B0172). Allolithocholic acid is a dual GPBAR1 agonist (EC50 = 2.7 µM) and RORgammat inverse agonist (IC50 = 3.4 µM). Allolithocholic acid modulates immune and metabolic pathways, regulates immune cell polarization, prevents M1 macrophage and Th17 CD4 cell polarization. Allolithocholic acid improves insulin sensitivity, reduces liver lipid accumulation, reverses liver immunological, inflammatory and metabolic signaling dysregulation, restores bile acid homeostasis, adipose tissue histopathology/function, and intestinal microbiota composition, modulates intestinal immunity. Allolithocholic acid can be used for the researches of cancer, inflammayion, immunology and metabolic disease[1][2].
Molecular Weight:
376.57
CAS Number:
[2276-94-0]
Formula:
C24H40O3
Target:
Drug Metabolite,G protein-coupled Bile Acid Receptor 1,Reference Standards,ROR
Application Notes:
MCE Product type: Reference Standards
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