GPP78 (CAY10618) is a potent Nampt inhibitor with an IC50 of 3.0 nM for nicotinamide adenine dinucleotide (NAD) depletion. GPP78 is cytotoxic to neuroblastoma cell line SH-SY5Y cells with an IC50 of 3.8 nM by inducing autophagy. GPP78 has anti-cancer and anti-inflammatory effects[1][2].
Molecular Weight:
439.55
Purity:
99
CAS Number:
[1202580-59-3]
Formula:
C27H29N5O
Target:
Autophagy,NAMPT
Application Notes:
MCE Product type: Reference compound
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