HTT-D3 is a potent and orally active huntingtin (HTT) splicing modulator. HTT-D3 acts by promoting the inclusion of a pseudoexon containing a premature termination codon (stop-codon psiExon), leading to HTT mRNA degradation and reduction of HTT levels. HTT-D3 reduces p-glycoprotein (P-gp) efflux, and can be uesd for Huntingtons disease research[1].
Molecular Weight:
404.48
CAS Number:
[2254502-89-9]
Formula:
C23H25FN6
Target:
P-glycoprotein
Application Notes:
MCE Product type: Reference compound
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