Indomethacin-d4 (Indometacin-d4) is a deuterium labeled Indomethacin. Indomethacin is a potent, blood-brain permeable and nonselective inhibitor of COX1 and COX2, with IC50s of 18 nM and 26 nM for human COX-1 and COX-2, respectively, in CHO cells[1]. Indomethacin disrupts autophagic flux by disturbing the normal functioning of lysosomes[2].
Molecular Weight:
361.81
Purity:
99.78
CAS Number:
[87377-08-0]
Formula:
C19H12D4ClNO4
Target:
Autophagy,COX,Isotope-Labeled Compounds
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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