ALK5-IN-8 is a potent inhibitor of TGFbetaRI (ALK5). ALK5-IN-8 Inhibits the phosphorylation of ALK5 on its downstream signaling proteins (Smad2 or Smad3) by blocking the binding of TGFbetaRI to ligands, thereby affecting or blocking TGF-beta signaling. ALK5-IN-8 has the potential for the research of various ALK5-mediated related diseases (extracted from patent WO2021190425A1, compound 1)[1].
Molecular Weight:
350.35
Purity:
98.21
CAS Number:
[2705900-81-6]
Formula:
C19H15FN4O2
Target:
TGF-beta Receptor
Application Notes:
MCE Product type: Reference compound
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