NLRP3/AIM2-IN-3, CAS [[1787787-60-3]]

Product Overview

• Article Name: NLRP3/AIM2-IN-3, CAS [[1787787-60-3]]
• Biozol Catalog Number: MCE-HY-144226
• Supplier Catalog Number: HY-144226
• Alternative Catalog Number: MCE-HY-144226-100MG,MCE-HY-144226-25MG,MCE-HY-144226-5MG,MCE-HY-144226-50MG,MCE-HY-144226-10MG,MCE-HY-144226-10MMX1ML
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

NLRP3/AIM2-IN-3 (compound 59) is a potent inhibitor with differential species specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. NLRP3/AIM2-IN-3 shows inhibitory efficacy against pyroptosis in THP-1 macrophages stimulated with LPS/nigericin, with an IC50 of 0.077 0.008 µM. NLRP3/AIM2-IN-3 disturbs the interaction of NLRP3 or AIM2 with the adaptor protein ASC and inhibited ASC oligomerization[1].

Product Properties

• Molecular Weight: 266.29
• Purity: 98.23
• CAS Number: [1787787-60-3]
• Formula: C16H14N2O2
• Target: AIM2,NOD-like Receptor (NLR),Pyroptosis

Application Notes

• Application Notes: MCE Product type: Reference compound