Velneperit (S-2367) is an orally active neuropeptide Y (NPY) Y5 receptor antagonist that can penetrate the blood-brain barrier. Velneperit inhibits the appetite-stimulating and metabolism-inhibiting effects mediated by NPY. Velneperit selectively improves diet-induced obesity in mice. Velneperit enhances the expression of fear acutely by removing the inhibition of CeA Drd2 neurons. Velneperit can be used for the study of obesity[1][2][3].
Molecular Weight:
407.45
Purity:
99.21
CAS Number:
[342577-38-2]
Formula:
C17H24F3N3O3S
Target:
Neuropeptide Y Receptor
Application Notes:
MCE Product type: Reference compound
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