Glucokinase activator 3 is an orally active Glucokinase (GK) activator with an AC50 of 38 nM. Glucokinase activator 3 inhibits hERG channel and sodium channel in patch clamp assays. Glucokinase activator 3 exhibits high efficacy in reducing blood glucose in diet-induced obese (DIO) mice. Glucokinase activator 3 has the potential for the research of type 2 diabetes[1].
Molecular Weight:
612.65
Purity:
98.36
CAS Number:
[1001417-92-0]
Formula:
C26H33N2O9PS2
Target:
Glucokinase,Sodium Channel
Application Notes:
Reference compound
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