pan-HER-IN-2 (Compound C6) is a reversible, orally active pan-HER inhibitor with IC50 values of 0.72, 2.0, 8.2 and 75.1 nM against EGFR, HER4, EGFRT790M/L858R and HER2, respectively. pan-HER-IN-2 induces apoptosis and shows antitumor activities[1].
Molecular Weight:
444.71
Purity:
98.10
CAS Number:
[1639040-95-1]
Formula:
C19H15BrClN5O
Target:
Apoptosis,EGFR
Application Notes:
MCE Product type: Reference compound1
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