PDE4-IN-8 (Example 5) is a potent PDE4 inhibitor with an IC50 of 0.93 nM for PDE4B2.PDE4-IN-8 has little effect on IL13 (IC50=4.04 nM), IL4 (IC50=36.33 nM), IFNy (IC50=2394 nM)[1].
Molecular Weight:
327.18
CAS Number:
[2415085-45-7]
Formula:
C18H22BNO4
Target:
Interleukin Related,Phosphodiesterase (PDE)
Application Notes:
MCE Product type: Reference compound1
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