BRG1-IN-1 (Compound 11d) is a potent inhibitor of SMARCA4/BRG1. BRG1-IN-1 shows better efficacy than PFI-3 in sensitizing GBM cells to the antiproliferative and cell death inducing effects of Temozolomide in vitro. BRG1-IN-1 enhances the inhibitor effect of Temozolomide on the growth of subcutaneous GBM tumors[1].
Molecular Weight:
322.38
CAS Number:
[2616813-99-9]
Formula:
C20H19FN2O
Target:
SWI/SNF Complex
Application Notes:
MCE Product type: Reference compound
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