TRK/ALK-IN-1 (compound 21) is a potent and dual inhibitor of TRK and ALK. TRK/ALK-IN-1 in the enzymatic assays is in good accordance with anti-proliferative activity with IC50 values of 2.2, 9.3 and 38 nM towards TRKA, ALKWT and ALKL1196M, respectively. TRK/ALK-IN-1 has the potential for the research of cancer diseases[1].
Molecular Weight:
657.18
Formula:
C31H35ClF2N8O2S
Target:
Anaplastic lymphoma kinase (ALK),Trk Receptor
Application Notes:
MCE Product type: Reference compound
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