Pantothenate kinase-IN-1 is a PANK3 inhibitor with an IC50 of 0.51 µM. Pantothenate kinase-IN-1 acts as a pantothenate-competitive inhibitor, which occupies the pantothenate-binding site of PANK3 and binds to both protomers in the PANK3 dimer. Pantothenate kinase-IN-1 exhibits metabolic stability in mouse and rat plasma. Pantothenate kinase-IN-1 can be used in the research of pantothenate kinase-associated neurodegenerative diseases and metabolic diseases[1].
Molecular Weight:
363.46
Purity:
98.20
CAS Number:
[1024168-48-6]
Formula:
C21H25N5O
Target:
PANK
Application Notes:
MCE Product type: Reference compound1
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